Bloonberry Bush Pro is Special Agent Pro for the Bloonberry Bush. To unlock it the player must place down 50 Bloonberry Bushes; this costs a total of 2500. This Special Agent Pro adds "creepers", which pop out along the track every three rounds. These creepers are capable of growing up to fifteen thorns each, and further aiding the Bloonberry Bush as an effective road blockade.
- If the player reloads the game from the save slot, the creepers disappear.
- A bug is has been encountered on Clock where a player had placed a Bloonberry Bush Pro and then accidentally sold it, but the bloons still got popped at the place where Bush was.